ABSTRACT
Objective To study the clinical effect, safety of stains collapse of traditional Chinese medicine (TCM) combined with tumor necrosis factor-alpha (TNF-α) antagonist-a recombinant human tumor necrosis factor receptor:Fc fusion protein (rhTNF:Fc) and sulfasalazine (SSZ) in treatment of active ankylosing spondylitis (AS). Methods A total of 98 patients of AS of Gansu Provincial Hospital were divided into two groups in random, the western medicine group (rhTNF:Fc and SSZ, n=46) and the combining group (stains collapse of TCM, rhTNF:Fc and SSZ, n=52). The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), Patient Global Assessment (PGA), Visual Analogue Scale (VAS) of night pain, VAS of total pain, time of morning stiffness, TCM symptom score, distance between occipital and wall, distance between finger and ground, thoracic activity, Schober test, and erythrocyte sedimentation rate (ESR), C reactive protein (CRP), adverse reactions before and after treatment were observed and the clinical effect was evaluated in two groups. Results A total of 86 patients achieved the study finally, 45 patients in the combining group and 41 patients in the western medicine group. The effective rate of ASAS20 was better in the combining group than that in the western medicine group(χ2=4.814,P=0.028), the Bath ankylosing spondylitis disease activity index (BASDAI) 50 showed no significant difference between the two group (χ2=0.100,P=0.752). The total effective rate in the combining group than that in the western medicine group(χ2=3.873,P=0.049). In comparison with the same group before treatment, the above indicators were improved after treatment (P0.05). The adverse reactions showed no significant difference (P>0.05). Conclusions Stains collapse of TCM combined with rhTNF:Fc was more effective than single method in treatment of AS, it can alleviated the symptoms, body signs and body function, decrease indexes of inflammation, which has dramatic effect and good safety in clinic.
ABSTRACT
Normative ethics is an important ethic theory that has been applied in contemporary medical ethics as principles and rules.Normative ethics can guide the doctors and the nurses to do a right behavior in medical practice effectively,but at the same time it has some limitation.Those limitation are mainly about a conflict from different moral norms and a demand for too perfect moral realm,which make the doctors and the nurses often meet a moral dilemma,and sometimes their working enthusiasm would be dampened.Virtues ethics is a different ethic theory that has some advantage such as consistence,stability and flexibility,so it can give us a more wide space of mind to perfect our medical moral theory.If we wish benevolence,justice and other virtues come true widely in medical practice,we should to rethink our professional moral education and to set a series of good rules and regulations.I believe our country's doctors and nurses would take shape a prevalent professional virtue when virtue ethics have been accepted as a important ethic theory.
ABSTRACT
Objective To analyze the water quality of the swimming pools in Yinchuan City from 2002 to 2005 and to know the sanitary states of the swimming pools, so as to prevent water-born infection effectually. Methods pH, turbidity, carbamide, free chlorine residual, coli group and total bacterial count in the water samples were determined. Results 664 water samples were tested, 252 water samples were qualified(the rate was 37.93%). From 2002 to 2005, the rates of up to standard were 29.08%, 22.83%, 40.48% and 50.00%, the difference was significant(?2=30.74, P